The Relation Between Peripheral Blood Leukocyte Counts and Respiratory...
In this analysis of peripheral blood leukocyte counts in a random and representative adult population, we have observed the previously well-documented associations between asthma, IgE, and blood...
View ArticleClinical Aspects of Respiratory Muscle Dysfunction in the Critically III:...
When the load placed on the respiratory muscle pump exceeds its capacity, ventilatory failure ensues. This situation is ultimately fatal unless either medical therapy is able to reduce the load or...
View ArticleClinical Aspects of Respiratory Muscle Dysfunction in the Critically III:...
The focus of this article is on the capacity of the pump to respond to the load imposed by disease, Although pump performance is our main concern, it is relevant to consider how best to measure load in...
View ArticleClinical Aspects of Respiratory Muscle Dysfunction in the Critically III: The...
The respiratory muscle pump may be considered to have an inspiratory and expiratory component. Although the expiratory muscles are critical for an effective cough,’ their failure in isolation is not...
View ArticleClinical Aspects of Respiratory Muscle Dysfunction in the Critically III:...
Structurally, the respiratory muscles are skeletal muscles and are, therefore, vulnerable to the same diseases and physiologic processes as, for example, the quadriceps or adductor pollicis (AP)...
View ArticleClinical Aspects of Respiratory Muscle Dysfunction in the Critically III:...
Our current preference is to measure Tw Pdi. Unfortunately, the placement of esophageal and gastric balloons in intubated patients is not always possible without the use of sedative drugs (although we...
View ArticleClinical Aspects of Respiratory Muscle Dysfunction in the Critically III:...
Electrophysiologic data can be useful to assess the cause and prognosis of a phrenic nerve injury, but they cannot inform the investigator about the pressure-generating properties of the muscle. The...
View ArticleClinical Aspects of Respiratory Muscle Dysfunction in the Critically III:...
As previously noted, preexisting neurologic causes of neuromuscular dysfunction are not covered in this review; however, a summary of their causes is shown in Table 2. CINMAs Although Clarence Olsen...
View ArticleClinical Aspects of Respiratory Muscle Dysfunction in the Critically III:...
The causes of CINMAs are less well-established (for a fuller discussion see DeJonghe et al and Bolton); however, multiple organ dysfunction, often but not always sepsis related, does seem to be a...
View ArticleClinical Aspects of Respiratory Muscle Dysfunction in the Critically III:...
Once cardiac and pulmonary causes have been excluded, prolonged ventilator dependency is most likely to be due to undiagnosed acquired neuromuscular disease. The use of neuromuscular blocking drugs and...
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